It’s good at killing fleas that other treatments miss, but on its own, it’s not quite as fast-acting as Imidacloprid or Selamectin. The problem is that some fleas have begun developing a resistance to Fipronil and S-methoprene, so Pyriproxyfen was added. The latter two make up the formula for regular Frontline, which has long been one of the top flea treatments on the market. It has an ingredient called Pyriproxyfen in addition to two other active ingredients, Fipronil and S-methoprene. The formula is waterproof, so you don’t have to worry about the efficacy taking a dive if your cat wanders out into the rain (it only becomes waterproof once it soaks in, though, so don’t bathe them immediately after application).įrontline Gold’s ranking is somewhat paradoxical, as it’s just a tiny bit worse than the previous two treatments, yet it’s the first thing that you should try if either of those doesn’t work. It’s fragrance-free as well - your cat won’t smell after you put it on them. Imidacloprid, however, works much faster than the others, so you should see near-immediate results.Īlso, unlike many other formulas, it kills on contact the fleas don’t have to bite your cat for it to work. After a few days, most of the major flea insecticides have similar kill rates, as they’ll all eradicate over 99% of fleas. Now, please note that it kills fleas faster, not better. The active ingredient, Imidacloprid, kills fleas faster than any other chemical currently on the market, and it takes out eggs and larvae too.
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This flea treatment won’t kill everything under the sun like Revolution Plus will, but it’s like napalm to fleas. That said, you can swap the two around depending on what qualities you prefer. It’s easy to apply and only needs to be put on once a month, giving you hassle-free protection.Īdvantage II technically sits in the number-two spot on this list, but it’s likely even better at killing fleas than Revolution Plus, though it’s not as versatile. Revolution Plus also requires a prescription, which is a bit of a hassle (but speaks to just how powerful the formula is). Still, it can be disconcerting to see a flare-up after you’ve applied a treatment. That’s normal, and nothing to worry about - those fleas will die off before they can lay eggs, and the life cycle will be snuffed out. As a result, you may see a huge difference in the flea population the first few days after application, only to see a few more pop up a little while later. There’s one big thing that it doesn’t do, however: kill flea eggs and larvae. It’s basically a one-stop shop for parasite management, which is why we believe that it’s the best overall flea treatment for cats.
Its primary ingredient, Selamectin, kills fleas, ticks, ear mites, and various worms (including heartworms). It will start knocking off fleas in as little as 4 hours.Ī quick caveat: Revolution Plus is our top pick because it’s incredibly versatile. If you want to be sure that you’ve killed every last little biter on your cat, you’ll need to call in the big guns, and they don’t come more powerful than Revolution Plus.
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